This project is part of the EDCTP3 programme supported by the European Union
The SAFIRE project, funded by Global Health EDCTP3, is generating first-of-its-kind clinical evidence to improve malaria treatment in early pregnancy. In 2024, the estimated number of malaria cases climbed to 282 million, up from 273 million the previous year, with
SAFIRE is challenging the status quo in clinical research, where women in the first trimester of pregnancy have traditionally been excluded, leaving critical evidence and treatment gaps for malaria in pregnancy. To help make a trial like SAFIRE possible, researchers
Major milestone in Africa’s first-ever study assessing malaria treatments in early pregnancy Through the SAFIRE consortium, experts from Africa and Europe are closing a critical treatment gap for women in early pregnancy. Each year, over 12 million pregnant women are
Speakers and presentations Shaping the future: advancing equitable and ethical research to meet women’s therapeutic needs Location: Kigali Convention Center, Room MH3Date & time: Tuesday, 17 June from 16:30 to 18:00 Dr Stephanie Dellicour, Principal Research Associate, Liverpool School of
In a world first, a global consortium plans to undertake a Phase 3 clinical trial assessing antimalarial medicines in women in their first trimester of pregnancy The trial will evaluate the efficacy, safety, tolerability and cost-effectiveness of antimalarial drugs to
Malaria is a dangerous disease. One that, according to the World Health Organization, resulted in 249 million cases and 608,000 deaths in 2022 worldwide. For pregnant women, particularly those in their first trimester, it can cause serious complications, a concern for over 120 million women
Authors: Jenna Hoyt, Adélaïde Compaoré, Samba Diarra, Freddy Bikioli Bolombo, Susan Nayiga, Serge Henri Zango, Moussa Djimde, Stephanie Dellicour, Japhet Kabalu Tshiongo, Hypolite Muhindo-Mavoko, Abel Kakuru, Simon Kariuki, Hellen Barsosio, Kassoum Kayentao, Innocent Valea, Jenny Hill, and Maud Majeres Lugand
Malaria is one of the most serious infectious diseases affecting predominantly low- and middle-income countries, where pregnant women are among the populations at risk. There are limited options to prevent or treat malaria in pregnancy, particularly in the first trimester,
