Africa-Europe partnership to launch historic Phase 3 clinical trial in early pregnancy
Kisumu, Kenya and Geneva, Switzerland 10 July 2024. The Safety of Antimalarials in the FIrst TRimEster (SAFIRE) consortium, made up of scientific and social research experts in malaria in pregnancy, has today kicked off the preparation of a historic project: the first-ever Phase 3 clinical trial testing the efficacy and safety of antimalarials in women in their first […]
Re-orienting anti-malarial drug development to better serve pregnant women
Malaria is one of the most serious infectious diseases affecting predominantly low- and middle-income countries, where pregnant women are among the populations at risk. There are limited options to prevent or treat malaria in pregnancy, particularly in the first trimester, and existing ones may not work optimally in areas where the threat of drug resistance […]
Opinion: Malaria clinical research must include pregnant women
Malaria is a dangerous disease. One that, according to the World Health Organization, resulted in 249 million cases and 608,000 deaths in 2022 worldwide. For pregnant women, particularly those in their first trimester, it can cause serious complications, a concern for over 120 million women of childbearing age living in malaria-endemic areas. Malaria in pregnancy can result in maternal and neonatal mortality, miscarriage, […]